A Revolutionary Drug to Cure Acquired Chronic Disease
Millions of patients with acquired chronic disease live with debilitating symptoms and equivocal treatments that consume $4.1 trillion in annual healthcare costs (in the US).
The causes of ACD are unknown, but are generally assumed to be multifactorial, and attributed to genes, germs, or other environmental factors.
Acquired chronic diseases (ACDs) typically develop slowly and appear later in life, often after a period of good health.
They include diseases such as Parkinson’s, Alzheimer’s, dysautonomia, autoimmunity, chronic kidney disease, chronic pain, myalgic encephalomyelitis/chronic fatigue syndrome.
The prevailing approach has been to look for biomarker anomalies (compared to healthy people) and find treatments that can improve these biomarkers.
However, this approach only identifies what has changed in the body. It does not necessarily identify the root cause of that change. To date, research has not identified the underlying root cause.
pills Thousands of approved prescription drugs (19K+ in the US)
graph Modest efficacy
warning Limited by side effects
none No cures
The role of brain signals in ACD is unexplored.
brain They are circuit-specific and change constantly.
nerve For example, a dysregulated signal to the dopamine neurons in a Parkinson’s patient compromises their control over movement.
wave This can potentially cure ACD
Group 427321031
Cortene is developing a patent-protected, peptide-based treatment for brain-centric acquired chronic diseases.