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# Cortene

## Sitemaps

- [XML Sitemap](https://corteneinc.com/sitemap.xml): Contains all public & indexable URLs for this website.

## Posts

- [Acute Corticotropin-Releasing Factor Receptor Type 2 Agonism Results in Sustained Symptom Improvement in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome](https://corteneinc.com/acute-corticotropin-releasing-factor-receptor-type-2-agonism-results-in-sustained-symptom-improvement-in-myalgic-encephalomyelitis-chronic-fatigue-syndrome/) - Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex multi-symptom disease with widespread evidence of disrupted systems. The authors hypothesize that it is caused by the upregulation of the corticotropin-releasing factor receptor type 2 (CRFR2) in the raphé nuclei and limbic system, which impairs the ability to maintain homeostasis. The authors propose utilizing agonist-mediated receptor endocytosis
- [Cortene to Move Forward on New Drug for Chronic Fatigue Syndrome (ME/CFS)](https://corteneinc.com/cortene-to-move-forward-on-new-drug-for-chronic-fatigue-syndrome-me-cfs/) - In February of last year, Health Rising announced an unusual event was going to take place: a small drug company named Cortene was going to trial a new drug for chronic fatigue syndrome (ME/CFS). Cortene’s trial was unique in a number of ways. For one, it involved ME/CFS – a disease which rarely receives drug
- [[Part III] A New Drug for Chronic Fatigue Syndrome (ME/CFS): The Clinical Trial](https://corteneinc.com/part-iii-a-new-drug-for-chronic-fatigue-syndrome-me-cfs-the-clinical-trial/) - An Exploratory Drug Trial For ME/CFS In the next month or so, Cortene, a small drug development company, will do a very unusual thing – trial a new drug in chronic fatigue syndrome (ME/CFS). The first two parts of the series on this new drug covered how ME/CFS came to the attention of Cortene, why
- [[Part II] A New Drug & A New Hypothesis For Chronic Fatigue Syndrome (ME/CFS)](https://corteneinc.com/part-ii-a-new-drug-a-new-hypothesis-for-chronic-fatigue-syndrome-me-cfs/) - Part 1 introduced how Cortene became involved in chronic fatigue syndrome (ME/CFS), and introduced its hypothesis that a maladaptation within the limbic system, which shapes our response to stress, may underlie ME/CFS. The Cortene Way: New Drug to Be Trialed in Chronic Fatigue Syndrome (ME/CFS) Soon – Pt. I In Part II Health Rising takes
- [[Part I] The Cortene Way: New Drug to Be Trialed in Chronic Fatigue Syndrome (ME/CFS) Soon](https://corteneinc.com/part-i-the-cortene-way-new-drug-to-be-trialed-in-chronic-fatigue-syndrome-me-cfs-soon/) - Research funding for chronic fatigue syndrome (ME/CFS) has been poor at best but clinical trials have elicited a wholly different degree of disappointment altogether. Few clinical trials are ever done and those often involve alternative approaches. The six active clinical trials listed in clinicaltrials.gov, for instance, include treatments like acupuncture, moxibustion, oral rehydration and CoQ10.
- [The Cortene Chronic Fatigue Syndrome (ME/CFS) Drug Trial Begins](https://corteneinc.com/the-cortene-chronic-fatigue-syndrome-me-cfs-drug-trial-begins/) - Since February, Health Rising has described the development of a new drug produced for chronic fatigue syndrome (ME/CFS) by a small pharmaceutical company named Cortene in three blogs: The Cortene Way: New Drug to Be Trialed in Chronic Fatigue Syndrome (ME/CFS) Soon – Pt. I Cortene II: A New Drug & A New Hypothesis For

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## Categories

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